Pharmacology and the ADMET Process

Understand the fundamentals of Pharmacology and the ADMET Process 

The Pharmacology and the ADMET Process course provides a foundational understanding of the principles of pharmacology and the ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicology) of drugs. Students will learn about the mechanisms of drug action, drug targets, and how drugs interact with the body. Additionally, students will gain an understanding of the factors that influence the ADMET of drugs, including pharmacokinetics and pharmacodynamics. The course will also cover current topics in drug development and the regulatory process.

Note: This new course is scheduled to launch in Summer 2025. 

 

Topics

• Introduction to Pharmacology and ADME
• Pharmacokinetics: Absorption and Distribution
• Pharmacokinetics: Metabolism 
• Pharmacokinetics: Elimination and Excretion
• Pharmacodynamics: Drug-Receptor Interactions
• Pharmacodynamics: Signal Transduction and Secondary Messengers
• Pharmacodynamics: Tolerance, Dependence, and Adverse Effects (Toxicology) 
• Pharmacogenomics and Personalized Medicine 
• Case Studies and Drug Development Applications 

Learning Objectives

By the end of this course, students will be able to: 

• Describe the steps in the pharmacology and ADMET process and their relevance in drug development
• Analyze pharmacology data including ADME properties, PKPD relationships, and toxicology findings 
• Model human dose prediction based on analyses of pharmacology and toxicology data
• Make recommendations on pharmacology plans based on case studies 

Prerequisites

There are no required prerequisites for this course. A bachelor’s degree in the life or physical sciences or more than ten years of biopharmaceutical industry, academic, or clinical experience with a secondary degree will help. 
 

Format

This course is offered in an online asynchronous format. There are no set meeting times, however, students follow a weekly schedule and there will be deadlines to meet in terms of course requirements. This course cannot be completed at an accelerated rate.